Linear and branched glyco-lipopeptide vaccines follow distinct cross-presentation pathways and generate different magnitudes of antitumor immunity

HIGHLIGHTS

  • who: Linear et al. from the Laboratory of Cellular and Molecular Immunology, The Gavin Herbert Eye Institute, School of Medicine, University of California Irvine, Irvine, California, United States of have published the paper: Linear and Branched Glyco-Lipopeptide Vaccines Follow Distinct Cross-Presentation Pathways and Generate Different Magnitudes of Antitumor Immunity, in the Journal: (JOURNAL) of June/21,/2010
  • what: This work demonstrate that the linear HER-GLP-1 construct induced higher magnitude of epitope-specific IFN-c-producing CD8+ T-cell response while the branched HER-GLP-2 analogue preferentially induced stronger IgG antibody . . .

     

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