HIGHLIGHTS
- who: Yong Tang from the (UNIVERSITY) have published the article: Linear ubiquitination of cFLIP induced by LUBAC contributes to TNFα-induced apoptosis, in the Journal: (JOURNAL) of August/20,/2018
- what: The authors report that LUBAC-mediated M1-linked ubiquitination of cellular FLICE-like inhibitory protein (cFLIP), an anti-apoptotic molecule, contributes to tumor necrosis factor (TNF) ␣-induced apoptosis. The authors determined the molecular mechanism of RNF31 in the regulation of apoptosis pathway.
- how: These data indicated that Lys-351 and Lys-353 may play a redundant J. Biol. The results showed that . . .
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