Linking biosynthetic and chemical space to accelerate microbial secondary metabolite discovery

HIGHLIGHTS

• who: Sylvia Soldatou and colleagues from the Department of Chemistry, University of Aberdeen, Aberdeen, UE, School of Computing Science have published the Article: Linking biosynthetic and chemical space to accelerate microbial secondary metabolite discovery, in the Journal: (JOURNAL) of 24/04/2019
• what: The authors focus on approaches to experimentally validate links between a BGC and a secondary metabolite using synthetic biology techniques, such as genetic manipulation of BGCs.
• how: This approach using molecular properties predicted from genomic information to guide the search in chemical space termed peptidogenomics by Kersten et_al (Kersten et_al . . .
  

   

  

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