Linking changes in epithelial morphogenesis to cancer mutations using computational modeling

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  • who: Katarzyna A. Rejniak et al. from the University of South Florida College of Medicine, Tampa, Florida, United States of America, Division of Tumor Cell Biology, Beckman Research Institute of City of Hope have published the research: Linking Changes in Epithelial Morphogenesis to Cancer Mutations Using Computational Modeling, in the Journal: (JOURNAL) of August/26,/2010
  • what: As a case study the authors focused on MCF10A cells expressing an oncogenic mutant HER2-YVMA to quantitatively assess changes in cell doubling time cell apoptotic rate and cell sensitivity to ECM accumulation when compared to the parental . . .

     

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