Lipid droplet accumulation in β cells in patients with type 2 diabetes is associated with insulin resistance, hyperglycemia and β cell dysfunction involving decreased insulin granules

HIGHLIGHTS

  • who: Tomomi Horii et al. from the Children`s Hospital of Pittsburgh, of Pittsburgh, United States have published the research work: Lipid droplet accumulation in u03b2 cells in patients with type 2 diabetes is associated with insulin resistance, hyperglycemia and u03b2 cell dysfunction involving decreased insulin granules, in the Journal: (JOURNAL)
  • what: This study demonstrated that LDs in b_cells accumulated more in patients with type 2 diabetes than in normal glucose-tolerant subjects and that LD accumulation was associated with insulin resistance, hyperglycemia and decreased insulin secretion.

SUMMARY

    In human pancreatic . . .

     

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