Lipid-induced transcriptomic changes in blood link to lipid metabolism and allergic response

HIGHLIGHTS

  • who: Koen F. Dekkers from the (UNIVERSITY) have published the research: Lipid-induced transcriptomic changes in blood link to lipid metabolism and allergic response, in the Journal: (JOURNAL) of 10/06/2021
  • how: Next building on the previous work4 the authors implemented a comprehensive MR analysis to infer causal effects of lipid levels on transcription using multiple genetic variants as causal anchors that allowed the authors to systematically investigate potential pleiotropy using state-of-the-art methods1516. To evaluate the relevance of these findings the authors investigated whether the TG-affected genes were also linked . . .

     

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