HIGHLIGHTS
- who: Yonghao Sun and collaborators from the Fudan University, China have published the article: Lipid metabolism in ferroptosis and ferroptosis-based cancer therapy, in the Journal: (JOURNAL)
SUMMARY
Macroscopically, ferroptosis cells show swelling of the cytoplasm as well as organelles, Frontiers in Oncology frontiersin.org 10.3389/fonc.2022.941618 ACSL4 is an indispensable enzyme for lipid metabolism that catalyzes the binding of free long-chain fatty_acids to CoA and preferentially recognizes arachidonic acid, and acylates it, after which LPCAT3 catalyzes the acylated AA into PL. PUFA substrates are oxidized in the U . . .
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