Lipidome remodeling activities of dpa-ea in palmitic acid-stimulated hepg2 cells and the in vivo anti-obesity effect of the dpa-ea and dha-ea mixture prepared from algae oil

HIGHLIGHTS

  • who: March et al. from the Anhui Medical University, China have published the paper: Lipidome remodeling activities of DPA-EA in palmitic acid-stimulated HepG2 cells and the in vivo anti-obesity effect of the DPA-EA and DHA-EA mixture prepared from algae oil, in the Journal: (JOURNAL)
  • what: Excitedly, this work demonstrated that both DPA-EA and Celastrol displayed lipid-lowering activities in Pal-stimulated HepG2 cells. This study shows that antiinflammatory Nur77 modulators can decrease lipid accumulation by promoting lipolysis. The authors provide new insights into the intervention mechanism of Nur77-targeting . . .

     

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