HIGHLIGHTS
- who: Frédéric Darios from the University Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France, Equipe de Neurogénétique, Ecole Pratique des have published the paper: Lipids in the Physiopathology of Hereditary Spastic Paraplegias, in the Journal: (JOURNAL)
- what: In this review, the authors propose in a first part an overview of the various metabolic pathways that are altered by mutations in genes responsible for HSP and HSP-related disorders such as leukodystrophies presenting with spasticity. In a second part, the authors examine the consequences of altered lipid metabolism on cellular functions . . .
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