HIGHLIGHTS
- who: James Wood and collaborators from the University of Nottingham, Nottingham , RD, UK have published the article: Lipoprotein Deprivation Reveals a Cholesterol-Dependent Therapeutic Vulnerability in Diffuse Glioma Metabolism, in the Journal: Cancers 2022, 14, x FOR PEER REVIEW of /2022/
- what: The authors show that removal of exogenous cholesterol in the form of lipoproteins from culture medium was detrimental to the growth of two paediatric diffuse glioma cell lines KNS42 and SF188 in association with S-phase elongation and a transcriptomic program indicating dysregulated cholesterol homeostasis. The authors demonstrate lipoprotein dependency as a key . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.