Liquidcna: tracking subclonal evolution from longitudinal liquid biopsies using somatic copy number alterations

HIGHLIGHTS

  • who: Eszter Lakatos from the for Genomics and Computational Biology, Barts Cancer Institute, Queen Mary University of London, London, UK have published the article: LiquidCNA: Tracking subclonal evolution from longitudinal liquid biopsies using somatic copy number alterations, in the Journal: (JOURNAL) of August/20,/2021
  • what: The authors compare the results with ichorCNA, a state-of-the-art method for the analysis of low-coverage cfDNA samples, and show that liquidCNA achieves similar accuracy in estimating tumor purity, while also offering accurate reconstruction of subclonal structure, not available from other methods. The authors demonstrate that . . .

     

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