HIGHLIGHTS
- who: Liquiritin Attenuates Pathological and collaborators from the Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China, Hubei Key Laboratory of Metabolic and have published the article: Liquiritin Attenuates Pathological Cardiac Hypertrophy by Activating the PKA/LKB1/AMPK Pathway, in the Journal: (JOURNAL)
- what: To test this hypothesis, in this study the authors evaluated the effects of LQ in a mouse model of pressure overload-induced cardiac hypertrophy induced by aortic banding (AB). Since LQ increased cardiomyocyte cAMP levels, and LQ-mediated LKB1 phosphorylation was prevented after PKA inhibition, the authors propose that LQ . . .
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