Lithium promotes longevity through gsk3/nrf2-dependent hormesis

HIGHLIGHTS

• who: Jorge Iván Castillo-Quan from the Department University College Street, London WC E BT, UK have published the Article: Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis, in the Journal: (JOURNAL) of April/19,/2016
• what: The authors show that a drug approved for human use and healthspan. The authors demonstrate that extends lifespan female and male Drosophila when administered throughout adulthood or only later life. The authors show that lithium supplementation in the diet can modulate longevity, stress resistance, and metabolism in Drosophila through the inhibition of GSK-3.
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