Lithocholic acid alleviates deoxynivalenol-induced lethal cholesterol metabolic abnormalities in ipi-2i cells

HIGHLIGHTS

  • who: Yanwei Li and colleagues from the College of Animal Science and Technology, Yangzhou University, Yangzhou, China have published the paper: Lithocholic Acid Alleviates Deoxynivalenol-Induced Lethal Cholesterol Metabolic Abnormalities in IPI-2I Cells, in the Journal: Metabolites 2022, 659 of /2022/
  • what: The authors aimed to study the protective roles of CA and LCA administration on the DON-exposed intestinal epithelial cells (IPI-2I) and the underlying mechanisms involved in metabolism. The authors demonstrate that LCA restored the DON-induced cell apoptosis by reducing the cleaved caspase 3 and cleaved PARP-1 expression. Together . . .

     

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