HIGHLIGHTS
- who: Isabel Fernandes-Freitas and colleagues from the Department London, London, United Kingdom have published the Article: Live Birth in Sex-Reversed XY Mice Lacking the Nuclear Receptor Dax1, in the Journal: Scientific Reports Scientific Reports
- what: The authors show that a minority of these sex-reversed chromosomal-XY mice can undergo puberty, maintain pregnancy, and give birth to live offspring.
- how: To gain additional insight in to the observations on sex-reversal phenotypes the authors conducted post-mortem analysis of plasma hormone levels ovaries and hypothalamic neuropeptide gene-expression.
SUMMARY . . .
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