Live cell imaging supports a key role for histone deacetylase as a molecular target during glioblastoma malignancy downgrade through tumor competence modulation

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  • who: Aline Menezes et al. from the Instituto Ciências Biomédicas, Universidade Federal do Rio Janeiro, AvCarlos Chagas Filho, Bloco F Sala, Rio Janeiro, Brazil have published the paper: Live Cell Imaging Supports a Key Role for Histone Deacetylase as a Molecular Target during Glioblastoma Malignancy Downgrade through Tumor Competence Modulation, in the Journal: Journal of Oncology of 28/Dec/2018
  • what: The authors seek to investigate the impact of HDAC activity on GBM cell behavior and plasticity by live cell imaging. The authors propose that HDAC-mediated radiosensitization of GBM cells is due . . .

     

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