Liver kinase b1 regulates remodeling of the tumor microenvironment in triple-negative breast cancer

HIGHLIGHTS

  • who: Liver Kinase B et al. from the United States University of Ljubljana, Slovenia have published the article: Liver Kinase B1 Regulates Remodeling of the Tumor Microenvironment in Triple-Negative Breast Cancer, in the Journal: (JOURNAL)
  • what: Findings from the study demonstrate that LKB1 inhibits matrix gene and protein remodeling , suggesting that LKB1 may repress cancer cell-mediated matrix remolding. Matrix genes observed to be altered in the study have an association with a cancer stem-like phenotype, and LKB1 is associated with the repression of cancer stemness in the lung, gallbladder, and glioblastoma cancers . . .

     

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