Lmerseq: an r package for analyzing transformed rna-seq data with linear mixed effects models

HIGHLIGHTS

  • who: Brian E. Vestal from the Center for Genes, Environment, USA and Informatics have published the article: lmerSeq: an R package for analyzing transformed RNA-Seq data with linear mixed effects models, in the Journal: (JOURNAL)
  • what: As an example that illustrates how the choices of transformation, model structure, and testing procedure can drastically alter inference, the authors compare the results from the VST-lmerSeq pipeline to two similar methods that rely on the VOOM transform: DREAM from the VariancePartion package and rmRNAseq from the eponymous package . This study has been fully described in Braga . . .

     

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