HIGHLIGHTS
- who: LncRNA EPR regulates intestinal from the Diagnostic Sciences (DISC), University of Genoa, Genova, Italy, Center for Omics Sciences, IRCCS Ospedale San have published the research: LncRNA EPR regulates intestinal mucus production and protects against inflammation and tumorigenesis, in the Journal: (JOURNAL)
- what: Because of its high expression in the intestine in this study the authors have generated a colon-specific conditional targeted deletion (EPR cKO) to evaluate in vivo functions in mice. cKO mice display epithelium hyperproliferation impaired and secretion as well as inflammatory infiltration in the proximal portion of the large intestine. Mechanistically . . .
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