Lncrna lyplal1-as1 rejuvenates human adipose-derived mesenchymal stem cell senescence via transcriptional mirlet7b inactivation

HIGHLIGHTS

  • who: Yanlei Yang from the Medical College Hospital, Clinical Immunology Center, Chinese Academy of Education Key Laboratory, Beijing, China have published the article: LncRNA LYPLAL1-AS1 rejuvenates human adipose-derived mesenchymal stem cell senescence via transcriptional MIRLET7B inactivation, in the Journal: (JOURNAL)
  • what: The work provides new insights into the mechanism of MSC and indicates lncRNA LYPLAL1AS1 and miR-let-7b potential therapeutic targets in aging. The authors aimed to reveal whether MIRLET7B and its mature miRNA (miR-let-7b) are involved in LYPLAL1-AS1 repression hADSC senescence. The authors demonstrate that LYPLAL1-AS1 is . . .

     

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