Lncrna mhrt prevents angiotensin ii-induced myocardial oxidative stress and nlrp3 inflammasome via nrf2 activation

HIGHLIGHTS

  • who: Pinyi Liu et al. from the Jilin Provincial Key Laboratory of Radiation Oncology and Therapy, The First Hospital of Jilin University, Changchun, China have published the research: LncRNA MHRT Prevents Angiotensin II-Induced Myocardial Oxidative Stress and NLRP3 Inflammasome via Nrf2 Activation, in the Journal: Antioxidants 2023, 672 of /2023/
  • what: Based on the above studies, the authors aimed to explore whether MHRT can prevent Ang II-induced myocardial oxidative damage and NLRP3-mediated inflammation, as well as examined mechanisms targeting Nrf2. The study showed the NLRP3 inflammasome, probably by decreasing cellular ROS deposition . . .

     

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