Lncrna tincr impairs the efficacy of immunotherapy against breast cancer by recruiting dnmt1 and downregulating mir-199a-5p via the stat1-tincr-usp20-pd-l1 axis

HIGHLIGHTS

  • who: Qin Wang from the Breast-tissue specimens and clinical assessments Patients at the Harbin Medical University Cancer Center (HMUCC) with a histological diagnosis of breast cancer who had not received chemotherapy or radiotherapy before surgical resection were eligible for recruitment to this studyRNA was extracted from breast cancer and normal control tissues stored at , u00b0C immediately after resection. Paraffinembedded tissue sections were produced from tissue samples stored in, % formaldehyde at , u00b0C immediately after resection. This study was approved by and conformed to the clinical research guidelines of the Research Ethics Committee of Harbin Medical University Cancer . . .

     

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