Lncrna tp73-as1 promotes oxidized low-density lipoprotein-induced apoptosis of endothelial cells in atherosclerosis by targeting the mir-654-3p/akt3 axis

HIGHLIGHTS

  • who: Jia Ni from the Stomatological Hospital, Southern Medical University, of China have published the research work: LncRNA TP73-AS1 promotes oxidized low-density lipoprotein-induced apoptosis of endothelial cells in atherosclerosis by targeting the miR-654-3p/AKT3 axis, in the Journal: (JOURNAL)
  • what: We investigated the role of TP73-AS1 in the apoptosis of HAECs and revealed that TP73-AS1 downregulation effectively inhibited apoptosis of ox-LDL treated HAECs through regulating the miR-654-3p/AKT3 axis.
  • how: The results indicated that miR-654-3p was a putative target of TP73 . . .

     

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