HIGHLIGHTS
- who: Peiling Huang from the Department of Neurological Rehabilitation, Beijing Rehabilitation Hospital, Capital Medical University, Beijing, China, have published the research work: LncZFAS1 Inhibit MPP+-Induced Neuroinflammation Through TXNIP/MIB1 E3 Ubiquitin Ligase/NLRP3 Axis, in the Journal: (JOURNAL)
- what: LncZFAS1 is involved in inflammation and pyroptosis in PD through the TXNIP/MIB1 E3 ubiquitin ligase/ NLRP3 axis.
- how: The results showed that SH-SY5Y cells generated and activated NLRP3 to induce cellular pyroptosis revealing the role of NLRP3 and cells other than microglia in the neuroinflammatory response in PD. In the study . . .
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