HIGHLIGHTS
- who: Farr and collaborators from the University of Texas Health Science Center, San Antonio, Texas, USA Department of Medicine have published the research work: Local senolysis in aged mice only partially replicates the benefits of systemic senolysis, in the Journal: (JOURNAL)
- what: Using both genetic and SnC transplantation models to either eliminate p16Ink4a+ Sn cells in old age or induce an aging Sn milieu in bone in younger mice, the studies demonstrate that both Sn osteocytes and non-skeletal SnCs contribute to skeletal aging. The authors demonstrate that the SASP causes an alteration in lineage . . .
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