Locations of the regulatory sites for isocitrate dehydrogenase kinase/phosphatase*

HIGHLIGHTS

  • who: Stephen P. Miller from the (UNIVERSITY) have published the article: Locations of the Regulatory Sites for Isocitrate Dehydrogenase Kinase/Phosphatase*, in the Journal: (JOURNAL) of August/27,/1999
  • what: The authors demonstrate that the effectors controlling these activities belong to two distinct classes that differ in mechanism and in the locations of their binding_sites. The authors demonstrate that there are at least two mechanisms by which the IDH kinase/phosphatase is regulated. The authors focused the efforts on derivatives of IDH kinase/phosphatase having marked reductions in IDH phosphatase activity but retaining a near . . .

     

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