Long-lasting blood pressure lowering effects of nitrite are no-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase g1 a redox signalling

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  • who: Oleksandra Prysyazhna and collaborators from the Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, YD, UK have published the paper: Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase G1 a redox signalling, in the Journal: (JOURNAL)
  • what: The authors demonstrate that a single bolus application of nitrite induces long-lasting blood pressure lowering effects by generating H2O2 and persulfide species in the resistance vessels to activate PKG1a in an NO-independent manner. This study . . .

     

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