Long repeating (ttaggg)n single-stranded dna self-condenses into compact beaded filaments stabilized by g-quadruplex formation

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• who: Anirban Kar from the Magnetic tweezers preparation Flow cells were engineered with glass cover slides affixed with double-sided tape to an aluminum foundation that maximized SPM bead imagingTelomeric, strand, strand or mutant, strand ssDNA (, pM final) was mixed with bead formation buffer (, mM Tris-Cl, pH, .6, mM KCl). The combined sample was boiled for , min followed by snap chilling on ice for, h. Prior to attachment, the glass slides were treated with (3-aminopropyl) triethoxysilane followed by a, :, mixture of Biotin-PEG SVA to mPEG-SVA (Invitrogen). NeutrAvidin (, ␮M have published the research: Long . . .
  

   

  

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