Long-term culture of patient-derived cardiac organoids recapitulated duchenne muscular dystrophy cardiomyopathy and disease progression

HIGHLIGHTS

• who: August and colleagues from the University of Granada, Spain have published the research work: Long-term culture of patient-derived cardiac organoids recapitulated Duchenne muscular dystrophy cardiomyopathy and disease progression, in the Journal: (JOURNAL)
• what: The authors focused on mapping out the functionally enriched pathways based on the differentially upregulated genes in DMDCOs as compared to DMD-Iso-COs, as well as their main miRNA regulators.
• how: The results showed that hypertrophy and dilated cardiomyopathy networks shared the same gene set (50 nodes 49 edges) miRNA interactions . This adaptive process is based . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.