Long-term immune reconstitution and t cell repertoire analysis after autologous hematopoietic stem cell transplantation in systemic sclerosis patients

HIGHLIGHTS

  • who: Dominique Farge from the (UNIVERSITY) have published the paper: Long-term immune reconstitution and T cell repertoire analysis after autologous hematopoietic stem cell transplantation in systemic sclerosis patients, in the Journal: (JOURNAL)
  • what: The authors show sustained and higher clonal diversity of the TCR repertoire at long-term after transplant in both groups, irrespective of their long-term clinical response.
  • how: Data were analyzed using FACS Diva (BD Biosciences).

SUMMARY

    Recovery of CD3+ T_cell reconstitution was delayed with persistent CD4+ T_cell lymphopenia. The authors therefore designed this study . . .

     

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