Long-term in vitro recording of cardiac action potentials on microelectrode arrays for chronic cardiotoxicity assessment

HIGHLIGHTS

  • who: Giuseppina Iachetta from the Istituto Italiano di Tecnologia, Via Morego, Genova, Italy have published the Article: Long-term in vitro recording of cardiac action potentials on microelectrode arrays for chronic cardiotoxicity assessment, in the Journal: (JOURNAL)
  • what: The authors show that optoporation applied to microelectrode arrays enables measuring action potentials from human-derived cardiac syncytia for more than 1 continuous month and provides reliable data on chronic cardiotoxic effects caused by known compounds such as pentamidine. Archives of Toxicology 97:509-522 By exploiting the non-invasiveness of optoporation (Messina et_al 2015) and a . . .

     

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