HIGHLIGHTS
SUMMARY
The symptomatic effect of a BoNT injection wears off and re-injections become necessary at a recommended interval of 3-4 months. Single or multiple injections of BoNT may also lead to the development of short- and/or long-term effects such as muscular weakness and atrophy. Three months after the injection, treatment satisfaction was much better in the BoNT group while strength, assessed subjectively with the MRC (Medical Research Council ) scale, was not much lower than in the placebo group. In contrast, when muscular atrophy/mass was assessed with objective methods (MRI and . . .
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