Longitudinal evaluation of proton magnetic resonance spectroscopy metabolites as biomarkers in huntington’s disease

HIGHLIGHTS

  • who: Alexander J. Lowe from the (UNIVERSITY) have published the Article: Longitudinal evaluation of proton magnetic resonance spectroscopy metabolites as biomarkers in Huntingtonu2019s disease, in the Journal: (JOURNAL)
  • what: This study used 1H-MRS data obtained from 59 participants at baseline and 48 at longitudinal follow-up after 24 months. The authors aimed to establish if significant metabolic alterations are present in the putamen of Huntington`s disease patients, and if signifiu00ad cant associations exist between metabolite concentration and measures of clinical progression, including composite Unified Huntington`s Disease Rating Scale (cUHDRS) and DBS score . . .

     

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