Longitudinal immune profiling after radiation-attenuated sporozoite vaccination reveals coordinated immune processes correlated with malaria protection

HIGHLIGHTS

  • who: Fergal J. Duffy and colleagues from the Human Technopole, Italy Medical Sciences Division, University have published the research work: Longitudinal immune profiling after radiation-attenuated sporozoite vaccination reveals coordinated immune processes correlated with malaria protection, in the Journal: (JOURNAL)
  • what: The authors have further explored the dynamics of interferon response following RAS vaccination and observed that type I interferon was negatively associated with the initial establishment of adaptive memory, but positively correlated with memory expansion upon boosting. This work has revealed that the coordination of protection-associated peripheral blood responses is complex, highly variable . . .

     

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