Lonp1 and mthsp70 cooperate to promote mitochondrial protein folding

HIGHLIGHTS

• who: Chun-Shik Shin from the California Institute Newcastle University have published the research: LONP1 and mtHSP70 cooperate to promote mitochondrial protein folding, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors show that LONP1 plays a major role in mitochondrial protein biogenesis.

SUMMARY

A | https://doi.org/10.1038/s41467-020-20597-z lthough human mitochondria contain their own genome encoding 13 core subunits of the oxidative_phosphorylation (OXPHOS) machinery, the majority of the human mitochondrial proteome is encoded by the nuclear genome1,2. To this well-established protease function . . .

 



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