Loop dynamics of thymidine diphosphate-rhamnose 3′-o-methyltransferase (cals11), an enzyme in calicheamicin biosynthesis

HIGHLIGHTS

• who: Lu Han and collaborators from the Biosciences at Rice, Rice University, Houston, Texas, USA have published the article: Loop dynamics of thymidine diphosphate-rhamnose 3′-O-methyltransferase (CalS11), an enzyme in calicheamicin biosynthesis, in the Journal: (JOURNAL) of 18/02/2016
• what: The authors propose that the L2 loop functions as a gate facilitating and/or providing specificity for substrate entry or promoting product release. The analysis shows the L2 loop is indeed highly flexible in ways that are consistent with enzymatic turnover, whereas the highly conserved loops L1 and L3 have dramatically more . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.