Loss of dead end1 induces testicular teratomas from primordial germ cells that failed to undergo sexual differentiation in embryonic testes

HIGHLIGHTS

• who: Atsuki Imai from the DivisionNational University have published the Article: Loss of Dead end1 induces testicular teratomas from primordial germ cells that failed to undergo sexual differentiation in embryonic testes, in the Journal: Scientific Reports Scientific Reports
• what: The authors showed that deletion of Dnd1 from migrating PGCs led to the accumulation of PGCs that failed to undergo sexual differentiation in the embryonic testes and found that ECCs were visibly developed from a portion of them after E16.5.
• how: As it has been reported that ECCs highly express NANOG and lose . . .
  

   

  

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