Loss of human beta cell identity in a reconstructed omental stromal cell environment

HIGHLIGHTS

• who: Blandine Secco and colleagues from the Institut Cochin, Université de Paris, INSERM, CNRS UMR, Paris, France have published the research: Loss of Human Beta Cell Identity in a Reconstructed Omental Stromal Cell Environment, in the Journal: Cells 2022, 11, 924. of /2022/
• what: The authors aimed here at studying the paracrine effect of stromal cells isolated from subcutaneous and omental adipose tissue on human beta cells. The authors demonstrate here that soluble factors derived from stromal cells isolated from human adipose_tissue signal human beta cells through different pathways, such as STAT, SMAD and NFKB . . .
  

   

  

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