HIGHLIGHTS
- who: Hu00e9lu00e8ne Arnould et al. from the 601, France, Universitu00e9 de, France, University of Toronto, Tanz Centre have published the research work: Loss of prion protein control of glucose metabolism promotes neurodegeneration in model of prion diseases, in the Journal: (JOURNAL) of 22/09/2010
- what: This study shows that the deregulation of PrPC regulatory function towards glucose metabolism contributes to neurodegeneration in prion diseases. The authors provide evidence that PrPnull-1C11 cells displayed deep modifications in the expression level of enzymes involved in glucose metabolism with an up-regulation of the glycolysis pathway and . . .
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