Loss of serglycin promotes primary tumor growth and vessel functionality in the rip1-tag2 mouse model for spontaneous insulinoma formation

HIGHLIGHTS

  • who: Andrew Hamilton and collaborators from the Department of Medical Biochemistry and Microbiology, University have published the Article: Loss of Serglycin Promotes Primary Tumor Growth and Vessel Functionality in the RIP1-Tag2 Mouse Model for Spontaneous Insulinoma Formation, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0126688]. May 15, 2015 of October/17,/2014
  • what: For the first time the authors show that serglycin-deficiency affects orthotopic primary tumor growth and tumor vascular functionality of late stage carcinomas.
  • how: To further investigate the contribution of serglycin to tumor development the authors . . .

     

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