Loss of the drosophila m-aaa mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration

HIGHLIGHTS

• who: Gautam Pareek from the (UNIVERSITY) have published the research work: Loss of the Drosophila m-AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration, in the Journal: (JOURNAL)
• what: Official journal of the Cell Death Differentiation Association the work provides a foundation to apply the powerful genetic tools of Drosophila to study the mechanisms underlying the neurological diseases associated with SPG7 mutations in humans10,14-16. Given these findings, and the fact that CG2658 encodes the most closely related protein to paraplegin, the authors propose that this gene . . .
  

   

  

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