HIGHLIGHTS
- who: Hussam Husanie from the Mice Mice were purchased from the Jackson Laboratory (stock#, stock #01937876, and stock #00817977) and crossed to generate wild-type mice (Ptf1a-CreER have published the article: Loss of tumor suppressor WWOX accelerates pancreatic cancer development through promotion of TGFu03b2/BMP2 signaling, in the Journal: (JOURNAL) of 22/08/2022
- what: The authors investigated the contribution of WWOX ablation in mice to PDAC initiation and progression and provided evidence that WWOX deletion leads to the acceleration of acinar to ductal metaplasia (ADM), PanIN lesion formation, and PDAC development by altering . . .
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