Low concentrations of oxidized phospholipids increase stress tolerance of endothelial cells

HIGHLIGHTS

SUMMARY

    Unexpectedly, the authors found an activity of OxPLs that had never been characterized before, namely their ability to protect endothelial cells (ECs) from cellular stress induced by biological and chemical factors. Phospholipids purchased from Avanti Polar Lipids (Alabaster, AL, USA) were: 1,2dimyristoyl-sn-glycero-3-phosphocholine (DMPC), 1-palmitoyl-2-hydroxy-sn-glycero-3phosphocholine (Lyso-PPC), 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (Lyso-PPE), 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoglycerol (Lyso-PPG), 1-oleoyl-2hydroxy-sn-glycero-3-phosphate (Lyso-OPA), 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoinositol . . .

     

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