HIGHLIGHTS
- who: Adenike O. Adekeye and collaborators from the Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham , RD, UK have published the research: Low-Density Lipoprotein Pathway Is a Ubiquitous Metabolic Vulnerability in High Grade Glioma Amenable for Nanotherapeutic Delivery, in the Journal: Pharmaceutics 2023, 599 of /2023/
- what: The authors determined LDL receptor (LDLR) expression in HGGs using immunohistochemistry on tissue microarrays from intra- and inter tumour regions of 36 adult and 133 paediatric patients to confirm LDLR as therapeutic target.
- how: The authors analysed expression levels in three representative cell line . . .
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