Low-dose exposure to pbde disrupts genomic integrity and innate immunity in mammary tissue

HIGHLIGHTS

  • who: BDE- and collaborators from the University of Florida, United States have published the paper: Low-dose exposure to PBDE disrupts genomic integrity and innate immunity in mammary tissue, in the Journal: (JOURNAL)
  • what: Evidence continues to accumulate on how genomic instability triggers innate inflammatory responses, with much of the research focusing on the cyclic GMP-AMP Synthase - Stimulator of Interferon Genes (cGAS-STING) pathway (Ablasser and Chen, 2019; Motwani et_al, 2019; Decout et_al, 2021).
  • how: Data was collected with instrument manufacturer-supplied software (Thermo Xcalibur). Given the associations among antioxidant signaling oxidative . . .

     

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