Low-dose ganciclovir ameliorates dextran sulfate sodium-induced ulcerative colitis through inhibiting macrophage sting activation in mice

HIGHLIGHTS

• who: November and collaborators from the Minzu University of China, China have published the research: Low-dose ganciclovir ameliorates dextran sulfate sodium-induced ulcerative colitis through inhibiting macrophage STING activation in mice, in the Journal: (JOURNAL)
• what: Subsequently, the authors aimed to explore the effects of low-dose GCV on STING activation caused by selective STING agonists 10carboxymethyl-9-acridanone (CMA), 5, 6-dimethylxanthenone-4acetic acid (DMXAA), and 2, 3-cGAMP (an endogenous agonist of STING) in RAW264.7 cells. All other chemicals used in the study were of analytical grade and obtained from commercial . . .
  

   

  

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