HIGHLIGHTS
- who: -hydroxy- and colleagues from the College of Life Sciences and Biotechnology University have published the paper: Low-dose UVB irradiation stimulates matrix metalloproteinase-1 expression via a BLT2-linked pathway in HaCaT cells, in the Journal: (JOURNAL)
- what: The authors demonstrate that BLT2, a cell surface receptor for LTB4 and 12(S)-HETE, plays a critical role in UVB-mediated MMP-1 upregulation in human HaCaT keratinocytes. The authors provide evidence suggesting that BLT2-mediated MMP-1 upregulation occurs through a signaling pathway dependent on ROS production and the subsequent stimulation of ERK. Based . . .
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