Low-frequency nnrti-resistant hiv-1 variants and relationship to mutational load in antiretroviral-naïve subjects

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  • who: Shaili Gupta 1 et al. from the Yale University School of Medicine, New Haven, CT, USA have published the article: Low-Frequency NNRTI-Resistant HIV-1 Variants and Relationship to Mutational Load in Antiretroviral-Naïve Subjects, in the Journal: Viruses 2014, 6, 3428-3437 of 27/06/2014
  • what: In this study, low-frequency variants possessing major NNRTI-resistance mutations were identified in 25.5% of ARV-naïve HIV-infected subjects. In this study, a strong correlation between NNRTI-resistant variant frequency and mutational load was identified; however, variants at low frequency . . .

     

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