Low nephron number induced by maternal protein restriction is prevented by nicotinamide riboside supplementation depending on sirtuin 3 activation

HIGHLIGHTS

  • who: Anna Pezzotta and colleagues from the Kilometro Rosso, Bergamo, Italy have published the article: Low Nephron Number Induced by Maternal Protein Restriction Is Prevented by Nicotinamide Riboside Supplementation Depending on Sirtuin 3 Activation, in the Journal: Cells 2022, 11, x FOR PEER REVIEW of 20/09/2022
  • what: This study explored whether SIRT3 stimulation by means of with (NR) a precursor of the SIRT3 co-substrate adenine dinucleotide (NAD+ ) was able to improve in a murine model of a protein (LP) diet. The authors show that a nephron number deficit and impaired renal architecture . . .

     

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