Low production of 12α-hydroxylated bile acids prevents hepatic steatosis in cyp2c70-/- mice by reducing fat absorption

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  • who: Rumei Li from the DepartmentUniversity of Center Groningen, Groningen, The Netherlands have published the Article: Low production of 12α-hydroxylated bile acids prevents hepatic steatosis in Cyp2c70-/- mice by reducing fat absorption, in the Journal: Microbiome analysis DNA was extracted from cecal contents of both male and female Cyp2c70-/- mice and WT controls after 12 weeks of WTD feeding. 16S sequencing of V4 region was performed on an Illumina HiSeq platform (Novogene, Hong Kong, China) as previously described (1). Briefly, an operational taxonomic unit (OTU) table with 1,502 OTUs was generated by screening OTUs in . . .

     

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